FDA approved new opioid drug called Dsuvia

原创编译 2018-11-10

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Sherley 原创编译

FDA approved new opioid drug called Dsuvia

Whit: Welcome back to GMA and to today’s “Weekend Download”.
A powerful new opioid are hitting the market, the FDA just approved the drug called “Dsuvia”, acknowledging the opioid crisis in the nation but saying that this drug filled an important but limited unmet medical needs. Joining us now with more about this.
This is ABC’s chief medical correspondent Dr Jen Ashton. Always great to have you with us.
欢迎收看GMA ，下面进入我们的“周末下载”（节目名称）
最近一种烈性很强的类鸦片药物在市场上畅销，美国食品及药物管理局(FDA)刚刚审核通过该药物，并将其命名为“Dsuvia”，尽管FDA承认这种药物可能在国内引起类鸦片药物危机，但他们也认为这种药物的出现填补了一些医学需求方面的空白，在这之前，这些需求虽然非常重要，却因资源有限，得不到满足。
现在，我们一起来深入了解下这种药物。这位是ABC 新闻的首席医学记者珍.阿什顿医生，非常欢迎你。

Jen: Good to be here.
我很高兴。

Whit: There is so much controversy over this drug even within the FDA, what can you tell with us about Dsuvia?
即使是在FDA内部，大家对此也这种药物也有诸多意见，您能和我们聊聊“Dsuvia”么？

Jen: Well, let me tell you about this drug, it’s small, it’s strong, and it’s about a thousand times more powerful than morphine. It’s in the opioid class of medication, and it’s really designed for use in the acute pain settings. So makers of the drug said the battlefield situation, emergency room situation , short term use and in medically supervised settings, projected annual sales of this is $1.1billion.
当然，这种药物体积很小，烈性却很强，甚至比吗啡还要强力1000倍，它属于类鸦片类。Dsuvia的研制者说，在战场上，急救室中，人们会经历剧痛，为了短期抑制这种剧痛，他们研制出了这种药物，当然，要在监管下才可使用这种药物。其年销售额预计达到11亿美元。

Whit: Wow, so people stand to make a lot money from this. We talked about the controversy, but what are the risks and benefits to a strong opioid like this.
那他们可以从中赚一大笔钱了。既然我们谈论了对这种药物的争议，接下来我想问问这种药物能给人们带来什么风险和好处呢？

Jen: Well. First of all, let’s start with the proposed benefit. It’s important to treat pain both acute and chronic. When you talk about this medication, it comes in an oral form, something called ODT. So you don’t have to swallow a pill, it literally dissolved in you mouth and has more rapid route of administration than say the intravenous or IV drugs.
Risks, any drug in the opioid class suppressed respiration and can stop your breathing, that can happen in the first time, that can be fatal. That how people died of opioid overdoses. So when you talk about new drugs like this., potential for abuse is there.
首先，我们来谈谈可能的好处，Dsuvia 对于抑制急性和慢性疼痛都能起到很大作用。这种药物一般都是口服的，人们一般称其口腔崩解片（ODT），服用这种药物时，你不用将其吞下，它会自动在你口腔中溶解，药效比静脉注射类的药物还要快。
至于风险，类鸦片药物对于呼吸系统有抑制作用，因此可能会阻止你的呼吸，人们在第一次使用该药物可能就会有这种风险，一旦出现，即是致命的。这就是为什么人们过量使用类鸦片药物会有死亡风险。这也是在使用新型药物的风险所在。

Whit: You talked about safety concerns. Specifically for patients and doctors, though, was this drug this strong?
您谈到了一些安全问题，那对于病人和医生而言，这种药物是不是也这样烈性呢？
Jen: Well,listen, it’s important to treat pain, it is the key, but it is important to treat it safely. Now many people in this area of pain management are thinking that we need to investigated other class of pain medication to make it safer. You know a lot of people are saying this is adding gasoline to the fire of major opioid epidemic.
Dsuvia在抑制疼痛方面有非常重要的作用，甚至是关键作用，但是更重要的是，我们要安全地使用这种药物。现在很多研究疼痛管理的领域的人都认为我们应该研制出其他类别的更加安全的止痛剂。很多人都说Dsuvia的出现时在类鸦片流行病上火上浇油。
Whit: People need to do their homework and epidemic impact thousands.
人们真的要在这些方面多做功课，（毕竟）类鸦片流行病影响了数千人。
Jen: Absolutely.
确实是。
Whit:Dr Jen , always happy to have you with us.
谢谢，珍医生。

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